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Nicoflex application. Ointment Nikoflex. Indications for use, reviews, analogues, contraindications. Combined drug - affordable price

An obligatory element of therapeutic care for diseases of the musculoskeletal system or sports are external preparations of irritating, absorbable and analgesic action. About Nikoflex ointment instructions for use will tell in detail about the composition, mechanism of action and the rules for taking this drug.

Pharmacological properties of the drug

The therapeutic effect of Nikoflex is due to a combination of several active pharmacological substances that simultaneously act on various links in the pathogenesis of a disease or pathological process. The classifier of pharmacotherapeutic groups classifies Nikoflex as a local irritant.

Due to the properties of its active ingredients, the ointment has the following local effects:

  • annoying- excites sensitive nerve endings (receptors located in the upper layers of the skin and perceiving the impact of various kinds of stimuli), initiates a flow of impulses to the brain and spinal cord, accompanied by a local and reflex reaction in the form of trophic effects, vasodilating and distracting effects;
  • anesthetic- weakens or completely stops pain in the affected area of ​​​​the body by stimulating the production of opioid peptides with analgesic effects, activating the pain relief system that regulates the perception of pain and suppresses it at various levels. The analgesic effect is also enhanced by the distracting effect of the thermal effect felt when applying the ointment;
  • anti-inflammatory- reduces or removes the inflammatory process, eliminates its clinical manifestations. The effect is achieved by a violation of the biosynthesis of prostaglandins - regulators and mediators of the development of inflammation and pain, a decrease in capillary permeability, and inhibition of energy supply to tissues in the pathological focus. As a result, the hyperemic area limited by inflammation decreases in volume, redness, swelling subside, pain sensations that appear when touching this place disappear;
  • absorbable- activates natural metabolic processes in the body that improve surface blood supply, provide tissue cells with oxygen and nutrients, which accelerates regeneration, helps restore the functionality of affected tissues, promotes the resorption of hematomas, skin thickening at the site of injury, reduces swelling.

Composition, release forms

The holder of the registration certificate Nikoflex is the Hungarian company CJSC Medimpex, Budapest. The drug is manufactured and supplied to the Russian market by Reanal, Hungary. Under the trademark Nikoflex, a single dosage form is produced - an ointment intended exclusively for external (cutaneous) use. The instruction describes the appearance, composition of the drug and the dosage of the active ingredients. The manufacturer reports that the ointment is soft, white in color, has a dense, homogeneous creamy consistency and a specific medicinal (according to patients, a little unpleasant) smell. Packed in 50 g aluminum tubes, equipped with a plastic screw cap. The tube, together with the instructions, is packed in a cardboard box.

The composition of the ointment includes medicinal substances - a combination of 3 active compounds and additives - a number of auxiliary ingredients:

  • ethylene glycol (hydroxyethyl) salicylate 9 g - a product of the interaction of salicylic acid and dihydric alcohol, has a pronounced anti-inflammatory, weak irritant, analgesic, antirheumatic effect;
  • ethyl nicotinate 2 g - a derivative of nicotinic acid, expands the capillaries of the epithelium and subcutaneous tissue, improves microcirculation, warms up tissues, has a resolving effect;
  • capsaicin of natural origin 15 mg - an alkaloid obtained from the processing of hot capsicum, affects the pain sensors located in the skin, causing irritating and analgesic (distracting) effects;
  • propyl and ethyl esters of para-hydroxybenzoic acid - preservatives, antifungal agents;
  • liquid, oily paraffin (medical vaseline oil) and white vaseline - the fatty base of the ointment;
  • highly purified water, denatured 96% ethyl (wine) alcohol - solvents;
  • sodium lauryl sulfate - anionic surfactant;
  • lavender essential oil - wound healing, antiseptic, anti-inflammatory agent, relieves redness and peeling of the skin;
  • cetearyl (cetylstearyl) octanoate - softening agent, reduces dryness of the skin.

How does Nicoflex ointment work?

The active substances of the drug quickly and easily overcome the outer layer of the skin, penetrate into the inner, deeper layers - the dermis, subcutaneous fat, muscle and bone tissue. Both epithelial (integumentary) and underlying connective tissue are sensitive to the action of Nikoflex. The effect develops quickly - relief occurs within a few minutes, but, according to patient reviews, Nikoflex ointment is characterized by a short-term effect.

The drug copes even with severe pain, fills the diseased area of ​​​​the body with pleasant warming warmth, a slight burning and tingling sensation, this effect lasts for an hour. For the complete elimination of pain symptoms, a course reception is required. At the same time, patients note that an increase in the amount of ointment directly does not affect the result of treatment in any way, it is the regularity of use that is important. Active components are practically not absorbed into the systemic circulation, which reduces the risk of side effects.

Availability, safety, speed, versatility of external use make Nicoflex a worthy alternative to drugs in tablets. The effectiveness of treatment is explained by a combination of various mechanisms of action.

What is the combination of natural components and chemical compounds combined in a single dosage form - Nikoflex ointment used for:

  • enhances blood supply at the site of application of the therapeutic composition, accelerates blood flow;
  • eliminates local hyperthermia, prevents tissue impregnation with exudate, reduces swelling of the joint, focal hyperemia caused by excessive filling of blood vessels in the damaged area;
  • fights with the consequences of bruises, injuries, damage to small capillaries and subcutaneous vessels - bruises, swelling;
  • relieves pain syndrome of various origin and severity, relieves aching joints, inflammation of muscle tissues, tendons;
  • warms up the musculoskeletal apparatus, brings it into working condition, relieves tension from nerve fibers, fatigue after physical overload, relaxes muscles, helps athletes before intense training;
  • inhibits the activity of enzymes provoking a disease state, prevents the strengthening of pathological manifestations, improves joint mobility, ensures quick recovery and painless motor activity.

Indications for admission

Nikoflex is a drug for symptomatic therapy. It is used to alleviate the symptoms of diseases of the musculoskeletal system, usually as an additional element of complex treatment, or as an independent drug for a slight bruise, minor sprain, or as a preventive measure.

What diseases is prescribed and what helps Nikoflex ointment:

  • arthralgia;
  • various types of myositis, myalgia, damage to the capsular-ligamentous apparatus, ruptures, other injuries;
  • all types of arthritis;
  • polyarthritis of subacute form or chronic nature;
  • deforming osteoarthritis;
  • periods of exacerbation of tendovaginitis;
  • chronic form of neuritis, neurological disorders - lumbago, sciatica, sciatica;
  • for warming up, increasing muscle tone, improving the degree of mobility and flexibility of the joints before the upcoming load or stretching.

Instructions for use

The treatment regimen and dosage of Nikoflex are determined based on the type and nature of the damage, the presence of a pain syndrome or inflammatory process, the size of the body area that needs to be treated with a medicinal composition. The prescription of the medicine is made by the attending physician. Without consulting a medical professional, it is necessary to adhere to the dosages established by the official instructions.

It is recommended to start therapy with a single application, gradually - after 2-3 days, increasing to 2 doses per day (preferably in the morning after waking up and in the evening). Athletes using injury prevention ointment should apply it immediately before warm-up.

  • Applied externally, applied to the surface of the skin in the zone of maximum pain, on areas of the body in need of warming up or directly above the pathological focus. Avoid places with impaired integrity of the skin - wound, burn, infected, inflamed areas. Protect the eyes, the area adjacent to them and other mucous membranes from getting particles of ointment on them.
  • The site of exposure to the ointment must first be cleaned (using warm soapy water) and dried dry.
  • A single dose for articular pathologies - 3-5 cm column of ointment, before sports training - 4-5 cm (corresponds to 1-2 g of ointment).
  • Distribute the composition in a thin layer, with weak rubbing movements for 3-4 minutes, waiting for complete absorption, which is signaled by a rush of blood to this place, fever, reddening of the skin, burning sensation.
  • The maximum duration of treatment is 10 days.
  • After completing the treatment procedure, wash your hands thoroughly with plenty of soapy water.
  • Do not combine treatment with Nikoflex ointment with the application of warm compresses!
  • It is advisable for patients with sensitive skin to refuse to take hot, skin-steaming baths before a treatment session or immediately after applying the medicinal composition.

Cases of overdose with the combined drug Nicoflex have not been identified. Increased caution should be observed in patients of childhood and adolescence - 6-18 years old or if the patient has symptoms of the aspirin triad.

The instruction prohibits the use of Nikoflex in case of:

  • individual intolerance to the components of the ointment;
  • children's age - 0-6 years;
  • pregnancy or breastfeeding.

Side effects

Nikoflex ointment is characterized by good tolerance. In extremely rare cases, it may develop:

  • allergic reaction of local type;
  • inflammation or irritation of the skin, swelling in the area of ​​​​impact of the ointment;
  • eczematous dermatitis;
  • angioedema.

Medical supervision is required for patients taking coumarin anticoagulants in parallel. The instruction does not warn about other clinically significant drug interactions.

The cost of the drug, analogues

Pharmacies release Nicoflex without presenting a prescription. The purchased drug should be stored in a tightly closed original container at a temperature not exceeding 25 degrees. Shelf life - 5 years. The average price of an ointment pack is:

  • tube 50 g - 280 rubles.

There are no complete structural analogues of Nikoflex. If replacement is necessary, you can choose a product for external use of a similar action. It is impossible to use Muscoflex as an analogue, because. it belongs to muscle relaxants of central action, and only local irritants can replace Nicoflex. The closest are preparations containing capsaicin - Espol brand ointment, pepper patches.

Also a replacement can be:

  • Kapsikam;
  • Bengay;
  • Bom Bengue;
  • Nyatoks.

Before using any drug, you must carefully study the instructions to exclude the presence of contraindications and find out the safe dosage. Uncontrolled use of local irritants is unacceptable.

Nikoflex ointment is a combined drug with analgesic, absorbable, irritating, anti-inflammatory properties. It has a warming, vasodilating, deeply penetrating effect, therefore, in medical practice, Nikoflex is used to eliminate pain syndromes. But before purchasing a drug, it is advisable to learn more about its pharmacological properties and contraindications.

Release form and composition of the ointment Nikoflex

Nikoflex warming ointment for external use is available in tubes of 50 grams. Each tube is packed in a cardboard box, which contains instructions for the use of the drug. The composition of the ointment contains three active ingredients: hydroxyethyl salicylate, ethyl nicotinate, capsaicin. The auxiliary components of the drug include:

  • methyl parahydroxybenzoate;
  • propyl parahydroxybenzoate;
  • lavender oil;
  • alcohol ethanol;
  • mineral oil;
  • sodium lauryl sulfate;
  • white soft paraffin;
  • cetostearyl alcohol;
  • purified water.

pharmachologic effect

Nikoflex ointment contains substances that expand and warm the superficial vessels at the site of application, causing a feeling of warmth, raising the temperature of the skin. The pharmacological action of the drug is associated with the anti-inflammatory activity of salicylate, the irritating properties of capsaicin, and the absorbable effect of ethyl nicotinate. The result comes immediately after application and lasts for at least an hour.

What ointment helps from: indications for use

According to the instructions for use, Nikoflex helps with sprains during sports training, inflammation of soft tissues of various etiologies, arthritis, rheumatism, arthrosis. An anti-inflammatory drug is used to treat diseases of various origins:

  • Neuritis.
  • Neuralgia.
  • Sciatica.
  • Myalgia.
  • Acute or chronic form of polyarthritis.
  • Incomplete remission of tendovaginitis.
  • Bruises, stretch marks, joint injuries.

Method of application and dosage

Nikoflex ointment is used externally. First, wash the affected area with warm water and soap and wipe dry, then apply the drug in a thin layer. According to the indications for the use of the drug, the recommended dosing regimen is as follows: for diseases of the joints, apply the remedy for the first three days 1 time per day, and then at regular intervals - 2 times.

If the drug is used by athletes to warm up the muscles before or after sports training, then it is applied to the skin with a strip of 3 to 5 cm long and carefully rubbed in, as with a massage. The course of treatment should be prescribed by the doctor individually, but, as a rule, the drug is used until the condition is relieved.

Contraindications

Uncontrolled use of the ointment, judging by the feedback from patients, can provoke an allergic reaction in the form of local skin irritation. Nikoflex should be used with caution in patients with bronchial asthma and adolescents from 6 to 12 years old so that there are no adverse reactions. Absolute contraindications include such conditions as pregnancy, the period of breastfeeding a child, children under 6 years of age, violations of the integrity of the epidermis, hypersensitivity to the active substances of the drug.

special instructions

It is not advisable to combine Nicoflex with warm compresses, as they do not interact. The simultaneous use of other drugs should be agreed with the doctor. Keep in mind during treatment that the drug enhances the effect of medical cups and the absorption of other drugs. If the ointment gets on the mucous membranes, they should be washed immediately with water to avoid irritation. If during the use of the drug allergic manifestations occur, then the treatment should be canceled and consult a doctor to adjust the therapeutic measures.

Price

How much does Nikoflex ointment cost? You can buy the drug at any pharmacy kiosk, as it is very popular among the population. The price of Nikoflex ointment in pharmacies varies from 200 to 300 rubles per tube of 50 grams. The cost of funds in the online store does not differ significantly, so it is not advisable to purchase it online and pay for delivery.

Analogues Nikoflex ointment

  1. . A close analogue of Nikoflex in terms of its effect on the skin and joints in case of pain syndromes, stretch marks, bruises. The drug is used in the treatment of deforming osteoarthritis, intercostal neuralgia.
  2. Camphart. It is indicated for sciatica, muscle pain of various origins, post-traumatic inflammation of the joints and soft tissues. Recommended for use in lumbago, arthralgia, neuralgia.
  3. Bom Bengue. Available in the form of an ointment for topical use. A drug is prescribed for diseases of the periarticular tissues, used in sports and for warming massages. The cheapest analogue of Nikoflex ointment.

Diseases of the osteoarticular and nervous system, in most cases, are accompanied by such unpleasant clinical signs as pain and inflammatory changes. The pharmaceutical industry offers various means that help to alleviate the patient's condition. As a first aid, a good result is observed against the background of the use of local forms. The advantages of such drugs are high efficiency, rapid relief of symptoms and the absence of a systemic effect.

Nikoflex ointment is a drug that many experts prefer at the present stage. It contains several active ingredients. The agent penetrates through the skin to the site of the pathological focus. After a short period of time, the patient notes an improvement in the condition and relief of negative manifestations.

The healing qualities of Nikoflex ointment appear immediately after applying the external agent. Unpleasant symptoms are leveled after the start of therapy during the first day.

Main Components

High efficiency of Nicoflex is provided by the following main components:

  1. Capsaicin - irritates the skin at the site of application of the ointment, which provides a warming and distracting result, helps to reduce pain.
  2. Ethyl nicotinate - expands the peripheral vessels of the skin, increases cellular metabolism, resolves pathological foci.
  3. Ethylene glycol salicylate - exhibits powerful anti-inflammatory properties due to the reduction of local edema and hyperemia.

Adjuvants

In addition to the main substances, Nikoflex ointment is supplemented with auxiliary chemical compounds that potentiate the action of the main medicinal components. Good adjuvant qualities are manifested due to:

  • methyl parahydroxybenzoate;
  • propyl parahydroxybenzoate;
  • lavender oil;
  • ethyl alcohol;
  • mineral oil;
  • sodium lauryl sulfate;
  • cetostearyl alcohol;
  • white soft paraffin;
  • purified water.

Release form

Pharmaceutical manufacturers produce Nikoflex in metal tubes of 50 grams. The dosage form is presented in the form of an ointment. This type of drug provides the optimal action of the components with a low risk of adverse reactions and systemic effects. Each carton contains instructions for the use of the substance.

Actions of the drug

Nikoflex ointment is a unique preparation that combines elements of synthetic and natural origin. The main substances have pronounced medicinal properties, such as:

  1. annoying;
  2. warming;
  3. analgesic;
  4. anti-inflammatory;
  5. vasodilating;
  6. absorbable.

Specialists widely prescribe a combined remedy for external use, Nikoflex ointment. You can name the following conditions, from which the drug helps:

  • Diseases of the nervous system - neuritis, neuralgia, manifestations of sciatica, lumbago.
  • The defeat of the soft and bone structures of the joints - arthritis, bursitis in acute and chronic form.
  • Clinical signs of tendovaginitis in the stage of incomplete remission.
  • Muscular pains during stretching and inflammatory changes.
  • Traumatic injuries of the musculoskeletal system - bruises, pain in other types of pathology.
  • As a warming agent after prolonged physical or sports activities.
  • To relieve pain in herpes zoster.

Application rules

In order for Nikoflex ointment to maximize its properties, you should follow the instructions for using the drug. The following recommendations can be found in the appendix:

  1. Before applying a local remedy, it is necessary to perform hygiene procedures. The skin is cleaned with soap and water.
  2. Moisture is removed with a clean towel so that the skin is dry.
  3. To apply a small amount of ointment in the volume of a pea, it is distributed over the surface with a thin layer.
  4. The time of action of the drug for 1 - 1.5 hours. Nicoflex is not removed from the skin surface.

In the pathology of the joints, the drug is used once for three days, and then twice a day. During sports training, the medicine is rubbed into the skin with massage movements, for this you need a strip of ointment up to 40 mm. In the complex treatment of other types of pathology, the doctor may prescribe Nikoflex 2-3 times a day.

Attention! The duration of application and the frequency of application of Nikoflex is determined by the specialist on an individual basis, depending on the type and severity of the disease.

Contraindications

There are situations in which Nicoflex warming ointment is not used. Before applying the ointment, you must familiarize yourself with some restrictions on use. The following contraindications are noted:

  • individual intolerance to the components of the drug;
  • children under 6 years of age;
  • the period of bearing a child;
  • when breastfeeding;
  • inflammation of the joints in the acute period;
  • open wound surfaces of the skin.

Important! The doctor should be careful when prescribing Nikoflex ointment to patients with bronchial asthma associated with the use of aspirin.

Side effects

Sometimes there may be adverse reactions in the form of skin irritation at the site of application of Nicoflex, which indicates an allergic predisposition. In rare cases, patients complained of chills and a short-term decrease in blood pressure. The symptoms leveled out on their own after the ointment was canceled.

There are special instructions when using Nicoflex:

  1. It is not recommended to combine the ointment with warming type compresses, given the lack of a positive effect.
  2. The doctor should be aware of the use of other drugs.
  3. The combined use of an external agent and medicinal cups, as well as other medicinal substances, can enhance the absorption of the components.
  4. If adverse reactions occur, stop using the ointment and consult a doctor.
  5. In case of contact with the mucous membrane of the eye, immediately rinse it with plenty of running water. If signs of irritation persist, a specialist should be consulted.

Price policy

Ointment Nikoflex refers to over-the-counter drugs. It can be freely purchased at any pharmaceutical institution. The drug is very popular among both doctors and patients. Therefore, usually there is no difficulty in finding a cure.

In pharmacy chains, you can find an external agent at a price of 200 to 300 rubles. There is an opportunity to buy ointment in the online store. The cost is almost the same as in a pharmacy. Therefore, each person chooses the most convenient way to purchase.

Analogues

Nikoflex ointment is an original combination drug that is effective in several directions on the pathological focus. Identical drugs are not found on the pharmacological market. However, there are analogues that have a similar mechanism of action. Among them, the most commonly prescribed:

  • - contains menthol as a locally irritating, distracting component and anesthetics - procaine, benzocaine, which penetrate into tissues and have an analgesic effect. Rubbing well helps with acute arthritis, myositis, sprains, bruises.
  • Percamf is a herbal preparation. The composition of the liquid includes tincture of capsicum and camphor alcohol, the combination of which gives an anti-inflammatory and analgesic effect. The main component irritates the nerve endings and skin tissues, which improves local blood circulation.
  • Evamenol is an exclusively natural remedy. Liniment contains menthol and eucalyptus oil, which reduce discomfort and pain, relieve swelling and inflammation, and also have an antiseptic effect. It is used as a local remedy, as an anesthetic, and is also widely used to treat pathologies of the upper respiratory tract. Suitable for use in children from two years of age.
  • Finalgon - consists of two vasodilating components - nicoboxil and nonivamide. Due to the warming effect, blood flow to the site of application of the ointment increases and the pain syndrome decreases. Children's age is a contraindication for the use of the remedy.
  • Camphort - cream contains four active substances - menthol, racemic camphor, methyl salicylate, benzyl nicotinate. The complex effect provides a quick vasodilating and distracting effect, increases local blood circulation and improves metabolic processes in tissues.

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Nicoflex has a vasodilating, warming and analgesic effect. Ointment Nikoflex has a pronounced anti-inflammatory and distracting effect. The active components of the drug, due to the effect on prostaglandins, have a direct anti-inflammatory effect, as well as an indirect vasodilating and warming effect. Capsaicin, which is part of the ointment, has a pronounced analgesic effect by influencing substance P in peripheral nerve fibers.
The drug penetrates deeply into adjacent tissues, due to the ability of hydroxyethyl salicylate to influence the structure of the epithelium.

The therapeutic effect of the drug develops quickly and lasts for at least 60 minutes. The drug reduces the intensity of the inflammatory process, relieves pain, improves joint mobility in patients with diseases of the musculoskeletal system.

The pharmacokinetics of the drug has not been studied.

Indications for use

A drug Nicoflex is used to eliminate pain in patients suffering from joint diseases, including arthrosis, spondyloarthrosis (including spondylarthrosis, which is accompanied by neuralgia) and arthritis.
The drug is prescribed to patients with myalgia of various etiologies, as well as during the recovery period in patients with tendovaginitis.
Nicoflex can be prescribed to athletes as an aid during warm-up.

Mode of application

Ointment Nikoflex designed for outdoor use. The ointment should be applied in a thin layer, rubbing lightly, on the affected area. Before using the drug, clean the affected area of ​​\u200b\u200bthe skin and wash your hands. After using the drug, you should also wash your hands thoroughly. Avoid getting the ointment into the eyes, mucous membranes and areas with damaged skin integrity. The duration of the course of treatment and the dose of the drug is determined by the attending physician individually for each patient.
Patients with diseases of the musculoskeletal system are usually prescribed 1 application of the drug per day for 3 days, after which they switch to the use of the drug 2 times a day. The duration of the course of the drug is determined depending on the severity of the disease.
Athletes are prescribed the application of 1-2 g of ointment immediately before the warm-up. It is recommended to rub the ointment for 3-4 minutes until the skin is slightly flushed.

Side effects

Nicoflex is usually well tolerated by patients. In isolated cases, mainly in patients with increased individual sensitivity, skin allergic reactions or Quincke's edema may develop.
When using the drug, the development of hyperemia, a feeling of slight tingling and burning of the treated area is noted, these effects are a consequence of the action of the drug and indicate the beginning of the development of a therapeutic effect.

Contraindications

Increased individual sensitivity to the components of the drug.
The drug is contraindicated for use during an active inflammatory process.
The drug is not used for the treatment of women during pregnancy and lactation, as well as for the treatment of children under the age of 18 due to the lack of reliable data on the safety and efficacy of the drug in these categories of patients.

Pregnancy

At the moment, there is not enough data on the safety of the drug during pregnancy.
If it is necessary to use the drug during lactation, you should consult with your doctor and decide on a temporary interruption of breastfeeding.

Interaction with other drugs

Without features.
It is not recommended to use the ointment on the same area of ​​the skin with other topical preparations.

Overdose

At the moment, there have been no reports of an overdose of the drug.

Release form

Ointment Nikoflex for external use, 50 g in tubes, 1 tube in a carton.

Storage conditions

Ointment for external use 50 g in tubes, 1 tube in a carton.

Compound

1g ointments Nikoflex contains:
Hydroxyethyl salicylate - 90 mg;
Ethyl nicotinate - 20 mg;
Capsaicin - 0.15 mg;
Excipients.

Main settings

Name: NIKOFLEX
ATX code: M02AC -