Magnelis in 6 pack. Why take Magnelis B6? Side effects include

21.10.2021

1 tablet contains: magnesium lactate 470 mg, pyridoxine hydrochloride 5 mg.

Excipients: sucrose, povidone (collidone 30), collidone SR (polyvinyl acetate, povidone, sodium lauryl sulfate, silicon dioxide), magnesium stearate, sodium carmellose (sodium carboxymethylcellulose), talc.
Shell composition: sucrose, kaolin (white clay), gelatin, acacia gum (gum arabic), white beeswax, carnauba wax, talc, titanium dioxide.
White or almost white film-coated tablets, round, biconvex.

pharmachologic effect

A drug that replenishes magnesium deficiency.
Magnesium is a vital element that is found in all tissues of the body and is necessary for the normal functioning of cells. Participates in most metabolic reactions, in the regulation of the transmission of nerve impulses and in muscle contraction, has antispasmodic, antiarrhythmic and antiplatelet effects.
The body receives magnesium from food. The lack of magnesium in the body can be observed in violation of the diet (diet) or with an increase in the need for magnesium (with increased physical and mental stress, stress, pregnancy, use of diuretics).
Pyridoxine (vitamin B6) is involved in many metabolic processes, in the regulation of the metabolism of the nervous system. Improves the absorption of magnesium from the gastrointestinal tract and its penetration into cells.
The content of magnesium in serum from 12 to 17 mg / l (0.5-0.7 mmol / l) indicates a moderate magnesium deficiency; below 12 mg / l (0.5 mmol / l) - about severe magnesium deficiency.

Indications for use

Established magnesium deficiency, isolated or associated with other deficiency conditions.

Mode of application

Adults are recommended to prescribe 6-8 tablets / day. Children over 6 years old (weighing more than 20 kg) - 4-6 tablets / day. The daily dose should be divided into 2-3 doses.
Treatment should be discontinued after normalization of the concentration of magnesium in the blood.
The drug should be taken during meals with a glass of water.

Interaction

With the simultaneous use of drugs containing phosphates or calcium salts, a significant decrease in the absorption of magnesium from the gastrointestinal tract is possible.
Magnesium preparations reduce the absorption of tetracycline, it is recommended to separate the intake of these preparations by a 3-hour interval.
Magnesium reduces the effect of oral thrombolytic agents, reduces the absorption of iron.
Vitamin B6 inhibits the activity of levodopa.

Side effect

From the digestive system: abdominal pain, constipation, nausea, vomiting, flatulence.
Allergic reactions: allergic reactions are possible.

Contraindications

- severe renal failure (CC less than 30 ml / min);
- phenylketonuria;
- children's age up to 6 years;
- Hypersensitivity to the components of the drug.
The drug should be used with caution in patients with moderate renal insufficiency, tk. there is a risk of developing hypermagnesemia.

Use during pregnancy and lactation
Clinical experience has not revealed a fetotoxic or teratogenic effect of the drug.
Magnelis® B6 can be used during pregnancy only on prescription.
Magnesium penetrates excreted in breast milk. The use of the drug during lactation and breastfeeding should be avoided.

Overdose

With normal kidney function, oral intake of magnesium does not cause toxic reactions. Magnesium poisoning can develop with kidney failure. Toxic effects mainly depend on the content of magnesium in the blood serum.
Symptoms: drop in blood pressure, nausea, vomiting, slow reflexes, anuria, respiratory depression, coma, cardiac arrest.
Treatment: rehydration, forced diuresis. Renal failure requires hemodialysis or peritoneal dialysis.

special instructions

If it is necessary to use the drug in patients with diabetes mellitus, it should be borne in mind that the tablets contain sucrose as an excipient.
In case of concomitant calcium deficiency, magnesium deficiency should be eliminated before calcium supplementation is started.

Magnelis B6 instructions for use are positioned as a drug (drug) intended to compensate for the lack of the trace element Mg (magnesium) in the body. The drug is effective in the development of an independent magnesium-deficient state, and in related deficiencies.

One of the vital nutrients is magnesium. In its absence or with a pronounced deficiency, many metabolic processes (including the main ones: carbohydrate, protein, phosphorus) cannot proceed normally. The vital activity of the organism at the cell level is disrupted, intestinal motility weakens, the efficiency of bile excretion processes decreases, neuromuscular excitation decreases, and the tone of the vascular wall is disturbed.

Mg deficiency is considered so unacceptable that with the simultaneous development of a lack of calcium and magnesium, the second is eliminated in the first place. The main symptoms of magnesium deficiency are:

irritability;
somnological disorders, although not pronounced;
increased heart rate;
fatigue that does not go away even after rest;
myalgia and paresthesia (tingling in the muscles);
spasticity of the walls of the digestive tract.

Magnelis B6 instruction describes how a drug that helps prevent the development or eliminate all these manifestations.

General characteristics of the drug

Tablets are small in size, white, convex on both sides, covered with a thin shell - this is the drug Magnelis B6. The medicine is intended for oral administration through the mouth (per os).

The main composition for drugs Magnelis B6 is pyridoxine hydrochloride or vitamin B6 (hence the final part of the name of the drug), in the amount of 5 mg and magnesium lactate (hence the basis of the name), in the amount of 470 mg.

All other substances described in the annotation are auxiliary and are needed to give the medication the appearance of a tablet and cover them with a shell. Magnesium has the main function of repaying the deficient state, while the vitamin helps to absorb this microelement to the walls of the patient's gastrointestinal tract, enhances its penetration into the tissues.

B6 is one of the vitamins involved in the functioning of the nervous system and in many metabolic functions of the body. Therefore, its participation in the process of restoring the body is far from ballast. The combination of magnesium + B6 is one of the most beneficial for the body.

In addition to the described remedy, there is also a tablet version of the drug - Magnelis B6 forte. This tool contains 2 times more vitamin B6 (10 mg) and a slightly increased amount of magnesium in the form of citrate, namely 618.43 mg, which corresponds to 100 mg Mg 2+.

Magnelis B6 and Magnelis B6 forte instructions describe how drugs with a passive mechanism of absorption by the walls of the digestive tract. Moreover, the absorption of the drug does not exceed half of its content in the tablet.

Contraindications and side effects

Long-acting drugs (forte) and a less saturated version of active ingredients should be taken with caution by people with renal insufficiency. With the normal functioning of the system of accumulation and excretion of urine, even when taking excessive doses, patients usually do not have problems. But people suffering from kidney pathology are at risk of "earning" magnesium poisoning.

In general, Magnelis B6 describes the instructions for use as a remedy with a minimum of contraindications, as well as its more powerful copy (forte). Not recommended for use:

persons with allergies / intolerance to any component of the drug;
patients with severe chronic renal failure;
glucose / galactose malabsorption syndrome;
children under 6 years of age (for forte - 12 years).

It should not be taken concomitantly with antiparkinsonian treatment (levodopa). If treatment with tetracyclines is necessary, the intake of the described medication and antibiotics should be separated by at least 3 hours. The annotation also advises lactating women to avoid taking the medicine, since magnesium actively penetrates into milk.

To undesirable "fellow travelers" Magnelis B6 and Magnelis B6 forte, instructions for use include drugs containing phosphates and calcium or its salts. These substances significantly impair the absorption of the main active component of the drug.

The main side effects when taking this medication include allergies (including skin manifestations) and epigastric pain, accompanied by nausea and vomiting. Both variants of a negative reaction, according to the annotation, are rare.

The main question of each patient is Magnelis B6, what is it for? It's no secret that gynecologists recommend magnesium preparations to almost all pregnant women.

Since Magnelis B6 does not prohibit the use of instructions during pregnancy, no fetotoxic effect was found in experimental studies to compensate for magnesium deficiency and “calm pregnancy”, this obstetrician actively introduced this drug into their practice. Magnelis B6 during pregnancy is especially relevant for diagnosed uterine hypertonicity.

What is Magnelis B6 prescribed for during pregnancy? This drug helps to preserve the viability of the fetus at small gestational periods. Maintain normal myometrial tone in the initial period of gestation, when the uterus is little susceptible to antispasmodics.

However, according to the annotation, the main indications for LS Magnelis B6 are deficient states, confirmed by analyzes.

Adult patients are recommended to take 6-8 tablets of medication per day, dividing the daily dose into 2-3 doses. Children from 6 years old and weighing more than 20 kg are recommended to take drugs with the same frequency, but in a daily dose of 4-6 tablets. The drug is taken with food, washing down the tablets with water.

How to take Magnelis B6 during pregnancy, you need to ask the obstetrician observing your gestation. Most often, the doctor prescribes Magnelis B6 during pregnancy with a dosage of 470 mg, 2 tablets 3 times a day, that is, the standard preim. But since the instructions for use during pregnancy do not give any recommendations on Magnelis B6, do not take this drug on your own. If you are taking calcium supplements, be sure to notify your doctor.

The cost of the drug

After reviewing HP Magnelis v6: instructions for use with indications, you will also want to know the cost of this remedy. Among similar medicines, this drug is one of the most economical. Magnelis B6 costs about 180-200 rubles, the same drug with the prefix forte 350-400 rubles.

Watch the video and you will find out what role magnesium plays in the human body.

Magnelis B6 - official instructions for use (tablets)

From a short video you will learn the main symptoms of a lack of magnesium in the body, as well as therapeutic and preventive methods for such vitamin deficiency.

Similar drugs

If you are looking for cheap analogues for HP Magnelis B6 - this is almost Sisyphean labor. Magnelis is one of the most budget funds of its group. Comparable with it in price Magnesium plus B6. In some pharmacy chains, this drug can be found cheaper than Magnelis. It costs from 125 rubles.

The main analogues for Magnelis B6 are drugs: and Magnistat. Both drugs are 2 times more expensive than the described remedy.

Summary of Reviews

Magnesium B6 or Magnelis which is better? This is one of the most frequently asked questions by patients. Can only compare with it another similar question: Magne B6 or Magnelis B6 which is better? According to the annotation, the preparations are identical. Therefore, the choice depends more on the personal preferences of the patient, his financial capabilities and respect / trust in the manufacturer. If you trust only foreign pharmaceutical companies, your choice is the French Magne B6. If you are satisfied with a domestic manufacturer - Magnelis B 6 or Magnesium plus B6.

According to patients who took Magne B6 or Magnelis B6, they noticed the difference only in price. On LS Magnelis B6 during pregnancy, the reviews are quite positive. Future mothers with hypertension and increased nervousness associated with a lack of magnesium note the positive effect of the drug. Some women during pregnancy who do not have such problems, but who were prescribed this drug, did not notice any effect and attributed the doctor's appointment to "reinsurance".

On Magnelis B6, reviews for neurosis are also quite positive if the drug is prescribed appropriately. But do not rush to self-medicate and take this remedy for insomnia, fatigue or depression. Perhaps your nervous breakdown is caused by completely different reasons.

On Magnelis B6, positive reviews are also shared by young mothers who are faced with a magnesium deficiency in young children, manifested in sleep disturbance and increased excitability. Children under six, of course, had to be given more expensive liquid forms. After reaching the age of 6, you can switch to an economical domestic drug. On Magnelis B6 forte, reviews are in the same vein. However, do not use this text and positive reviews on this medication as instructions for self-treatment. Be sure to check with your doctor!

Magnelis B 6 is a drug designed to compensate for the lack of magnesium in the body.

Release form and composition

The drug is produced in the form of coated tablets: round, biconvex, white or almost white (10 pcs in blister packs, in a carton pack of 3 or 5 packs; 60 pcs or 90 pcs in polymer jars, in a carton pack 1 bank).

Composition per 1 tablet:

active ingredients: vitamin B 6 (in the form of pyridoxine hydrochloride) - 5 mg, magnesium (in the form of magnesium lactate) - 470 mg;
auxiliary components: povidone, magnesium stearate, sodium lauryl sulfate, talc, silicon dioxide, sodium carmellose, polyvinyl acetate;
tablet shell: kaolin, acacia gum, talc, sucrose, carnauba wax, titanium dioxide, white beeswax.

Pharmacological properties

Pharmacodynamics

Magnesium is a vital element found in all tissues and organs of the human body. It takes part in many metabolic reactions, in the contraction of muscle fibers and in the regulation of the transmission of impulses through nerve cells. Magnesium has antiarrhythmic, antiplatelet and antispasmodic effects.

Magnesium enters the human body with food. A deficiency of this element occurs when there is a violation of the diet (for example, when dieting) or in conditions characterized by an increased need for magnesium (under stress, during pregnancy, during the use of diuretics, with excessive mental and physical stress).

Vitamin B 6 (pyridoxine) is also involved in many metabolic processes and in the regulation of the metabolism of the nervous system. Thanks to pyridoxine, the absorption of magnesium from the digestive tract and its penetration into the cells of the body improves.

The following levels of magnesium in serum indicate its deficiency:

moderate magnesium deficiency - 0.5-0.7 mmol / l (12-17 mg / l);
severe magnesium deficiency - less than 0.5 mmol / l (less than 12 mg / l).

Pharmacokinetics

About 50% of the accepted dose of magnesium is absorbed in the gastrointestinal tract. The drug is excreted mainly through the kidneys. Approximately 70% of the magnesium present in plasma undergoes glomerular filtration in the kidneys. Thereafter, it is 95–97% reabsorbed by the renal tubules.

Indications for use

Magnelis B 6 is used for established magnesium deficiency (both isolated and associated with other deficient conditions).

Contraindications

Absolute:

phenylketonuria (impaired metabolism of phenylalanine);
severe renal failure (creatinine clearance less than 30 ml / min);
children under 6 years of age;
hypersensitivity to the main or additional components of the drug.

Magnelis B 6 is prescribed with caution to patients with moderate renal insufficiency, since there is a risk of hypermagnesemia.

Magnelis B 6, instructions for use (method and dosage)

Magnelis B 6 tablets are taken orally, during a meal, with plenty of water (at least one glass).

The recommended dose for adults is 6-8 tablets per day. Children and adolescents aged 6-18 years (weighing more than 20 kg) are prescribed 4-6 tablets per day. The daily dose of the drug is divided into 2-3 doses.

After the normalization of the level of magnesium in the blood, treatment with the drug is stopped.

Side effects

The drug can cause the following undesirable side effects: vomiting, nausea, pain in the abdomen, increased gas formation, constipation, allergic reactions.

Overdose

In patients with normal kidney function, oral magnesium does not cause toxic reactions. Poisoning with this element can develop in people with kidney failure. Symptoms of intoxication depend on the concentration of magnesium in the serum. So, with an overdose of the drug, the following reactions may occur: vomiting, nausea, respiratory depression, a drop in blood pressure, a complete absence of urine in the bladder, slow reflexes, cardiac arrest, coma.

Treatment consists of forced diuresis and fluid replacement in the body. Patients with renal insufficiency are prescribed peritoneal dialysis or hemodialysis.

special instructions

When prescribing Magnelis B to 6 patients with diabetes, it should be borne in mind that the tablets contain sucrose as an auxiliary component.

With a concomitant calcium deficiency, it is first necessary to eliminate the lack of magnesium, only after that you can start taking calcium-containing drugs.

Influence on the ability to drive vehicles and complex mechanisms

There is no information on the effect of the drug on the patient's ability to drive vehicles and other mechanisms.

Use during pregnancy and lactation

In clinical studies, no teratogenic or fetotoxic effect of the drug on the fetus was revealed, however, during pregnancy, the use of Magnelis B 6 is possible only as directed by a specialist.

Magnesium passes into breast milk, so the use of the drug during breastfeeding should be avoided.

Application in childhood

Magnelis B 6 tablets are not prescribed for children under 6 years of age.

For impaired renal function

Severe renal failure is a contraindication to the use of the drug. With moderate renal insufficiency, it is prescribed with caution (due to the risk of hypermagnesemia).

drug interaction

When combined with drugs containing calcium salts or phosphates, there may be a significant decrease in the absorption of magnesium from the gastrointestinal tract.

According to the instructions, Magnelis B 6 can reduce the absorption of tetracyclines, so the interval between taking these drugs should be at least 3 hours.

Magnesium reduces the effectiveness of oral thrombolytic drugs and reduces the absorption of iron.

Pyridoxine inhibits the action of levodopa.

Analogues

Analogues of Magnelis B6 are: Magne B 6, Magnistad, Magnesium Plus B 6, etc.

Terms and conditions of storage

Store in a dark place, out of the reach of children, at a temperature not exceeding 25 °C.

Shelf life - 2 years.

A drug that replenishes magnesium deficiency in the body

Active ingredients

Release form, composition and packaging

◊ Coated tablets white or almost white, round, biconvex.

Shell composition: sucrose, kaolin (white clay), gelatin, acacia gum (gum arabic), white beeswax, carnauba wax, talc, titanium dioxide.

10 pieces. - cellular contour packings (3) - packs of cardboard.
10 pieces. - cellular contour packings (5) - packs of cardboard.
60 pcs. - polymer cans (1) - packs of cardboard.
90 pcs. - polymer cans (1) - packs of cardboard.

pharmachologic effect

A drug that replenishes magnesium deficiency.

Magnesium is a vital element that is found in all tissues of the body and is necessary for the normal functioning of cells. Participates in most metabolic reactions, in the regulation of the transmission of nerve impulses and in muscle contraction, has antispasmodic, antiarrhythmic and antiplatelet effects.

The body receives magnesium from food. The lack of magnesium in the body can be observed in violation of the diet (diet) or with an increase in the need for magnesium (with increased physical and mental stress, stress, pregnancy, use of diuretics).

Pyridoxine (B 6) is involved in many metabolic processes, in the regulation of the metabolism of the nervous system. Improves the absorption of magnesium from the gastrointestinal tract and its penetration into cells.

Pharmacokinetics

Suction

After taking the drug inside, the absorption of magnesium from the gastrointestinal tract is 50%.

breeding

It is excreted mainly by the kidneys. In the kidneys, after glomerular filtration, 70% of the magnesium present in it, its reabsorption in the renal tubules is 95-97%.

Indications

- Established magnesium deficiency, isolated or associated with other deficient conditions.

Contraindications

- severe renal failure (CC less than 30 ml / min);

- phenylketonuria;

- children's age up to 6 years;

- Hypersensitivity to the components of the drug.

With caution the drug should be used in patients with moderate, because. there is a risk of developing hypermagnesemia.

Dosage

Treatment should be discontinued after normalization of the concentration of magnesium in the blood.

The drug should be taken during meals with a glass of water.

Side effects

From the digestive system:, constipation, nausea, vomiting, flatulence.

Allergic reactions: allergic reactions are possible.

Overdose

Symptoms: drop in blood pressure, nausea, vomiting, slow reflexes, anuria, respiratory depression, coma, cardiac arrest.

Treatment: rehydration, forced diuresis. Renal failure requires hemodialysis or peritoneal dialysis.

drug interaction

With the simultaneous use of drugs containing phosphates or calcium salts, a significant decrease in the absorption of magnesium from the gastrointestinal tract is possible.

Magnesium reduces the effect of oral thrombolytic agents, reduces the absorption of iron.

Vitamin B 6 inhibits the activity of levodopa.

special instructions

If it is necessary to use the drug in patients with diabetes mellitus, it should be borne in mind that the tablets contain sucrose as an excipient.

Replenishing magnesium deficiency in the body is the drug Magnelis B6. Instructions for use suggest taking tablets for conditions associated with a lack of magnesium. Patient reviews and doctors' recommendations indicate that this drug helps with muscle cramps.

Release form and composition

Magnelis B6 is available in tablets for oral administration, convex on both sides, covered with a white protective film on the shoulder.

The drug is packaged in blisters of 10 pieces, 3 or 5 blisters in a cardboard box or 100 pieces in cans of polymeric material with instructions attached.

Each tablet of Magnelis B6 contains 470 mg of magnesium lactate and 5 mg of pyridoxine hydrochloride (vitamin B6). In addition to the main active ingredients, the composition of the drug includes a number of auxiliary substances.

They also sell an enhanced form of the drug Magnelis B6 Forte. The instruction informs about the doubled content of active elements in this preparation.

pharmachologic effect

Magnelis B6 is a drug that replenishes magnesium deficiency. Magnesium is a vital element that is found in all tissues of the body and is necessary for the normal functioning of cells. Participates in most metabolic reactions, in the regulation of the transmission of nerve impulses and in muscle contraction, has antispasmodic, antiarrhythmic and antiplatelet effects.

Pyridoxine (vitamin B6) is involved in many metabolic processes, in the regulation of the metabolism of the nervous system. Improves the absorption of magnesium from the gastrointestinal tract and its penetration into cells.

Why take Magnelis B6 (forte)?

Indications for the use of the drug include magnesium deficiency, isolated or associated with other deficiency conditions, accompanied by symptoms such as:

muscle spasms or pain, tingling sensation in the muscles;
increased fatigue;
gastrointestinal spasms;
minor sleep disturbances;
heart palpitations;
increased irritability.

Instructions for use

Magnelis B6, according to the instructions, is prescribed to patients over 16 years old, 2 tablets of the drug 3-4 times a day, depending on the severity of magnesium deficiency. The drug can be taken regardless of food, if necessary, grinding and drinking plenty of water.

The duration of the course of therapy is determined by a specialist and continues until the level of magnesium in the blood serum normalizes.

Contraindications

phenylketonuria;
children's age up to 6 years;
hypersensitivity to the components of the drug;
severe renal failure (CC less than 30 ml / min).

Side effects

Possible adverse reactions from the digestive system:

The development of allergic reactions may also be observed.

Children, during pregnancy and lactation

Clinical experience has not revealed a fetotoxic or teratogenic effect of the drug. Magnelis B6 can be used during pregnancy only on prescription. Magnesium penetrates excreted in breast milk.

The use of the drug during lactation and breastfeeding should be avoided. Contraindicated in children under 6 years of age.

special instructions

Patients with diabetes should take into account that the tablets contain sucrose as an auxiliary component. With frequent use of alcohol, laxatives, intense mental and physical stress, the need for magnesium increases, which can cause the development of magnesium deficiency in the body. In cases of concomitant calcium deficiency, magnesium deficiency should be corrected before calcium supplementation is started.

drug interaction

With the simultaneous use of the drug Magnelis B6 with Tetracycline, the absorption of the latter is reduced, as a result of which the therapeutic effect will be insufficient. If drug interaction is necessary, an interval of at least 3 hours should be maintained.

Magnesium prevents the full absorption of iron by the walls of the small intestine, so it is not recommended to combine Magnelis B6 with drugs for the treatment of anemia.

Under the influence of Pyridoxine, which is part of the drug, the therapeutic effect of Levodopa is inhibited.

Medicine analogs

According to the structure, analogues are determined:

Pikovit Complex.
Magne B6 forte.
Magnelact.
Magnesium plus.
Supradin Kids Junior.
Additive Magnesium.
Osteocare solution.
Vitrum Mag.
Asparkam Farmak.
Beauty tabs Elegant with calcium.
Multi tabs Active.
Vitrum forte Osteomag.
Magne B6.

Holiday conditions and price

The average price of Magnelis B6 (tablets No. 50) in Moscow is 305 rubles. The medicine can be freely purchased at pharmacies without a prescription from a doctor.

The optimum storage temperature of the drug should not be higher than 25 degrees. Keep tablets in a dry place away from children. The shelf life is 3 years from the date of manufacture, which is indicated on the package.

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